I have done some of the Southern parts of it, but not the whole thing. You'll definitely have no problem doing the southern half in late November (in fact, the daytime weather should be fantastic), but will possibly run into winter weather issues for the northern part. Even on the southern parts, expect very cold nights. When we camp in southern AZ in November the mornings are sometimes in the high 20s low 30s, even though the days are high 60s to high 70s